Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excess

Author:

Johnson K.,Terkeltaub R.

Publisher

Elsevier BV

Subject

Orthopedics and Sports Medicine,Biomedical Engineering,Rheumatology

Reference40 articles.

1. What does cartilage calcification tell us about osteoarthritis?;Terkeltaub;J Rheumatol,2002

2. Jr. Elevated inorganic pyrophosphate concentrations in synovial fluids in osteoarthritis and pseudogout;Silcox;J Lab Clin Med,1974

3. Upregulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification;Johnson;Arthritis Rheum,2001

4. Differential effects of aging on human chondrocyte responses to transforming growth factor beta: increased pyrophosphate production and decreased cell proliferation;Rosen;Arthritis Rheum,1997

5. Inorganic pyrophosphate in metabolic diseases predisposing to calcium pyrophosphate dihydrate crystal deposition;Doherty;Arthritis Rheum,1991

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