Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction-Reference-Cited by-同舟云学术

Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction

Published:2019-06 Issue:6 Volume:27 Page:965-976
ISSN:1063-4584
Container-title:Osteoarthritis and Cartilage
language:en
Short-container-title:Osteoarthritis and Cartilage

Author:

Kakiuchi Y.,Yurube T.^ORCID,Kakutani K.,Takada T.,Ito M.,Takeoka Y.,Kanda Y.,Miyazaki S.,Kuroda R.,Nishida K.

Funder

JSPS

Japan Orthopaedics and Traumatology Research Foundation, Inc

Publisher

Elsevier BV

Subject

Orthopedics and Sports Medicine,Biomedical Engineering,Rheumatology

Reference50 articles.

1. Epidemiological features of chronic low-back pain;Andersson;Lancet,1999

2. Lumbar disc disorders and low-back pain: socioeconomic factors and consequences;Katz;J Bone Jt Surg Am,2006

3. Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study;Livshits;Ann Rheum Dis,2011

4. Degeneration of the intervertebral disc;Urban;Arthritis Res Ther,2003

5. Nutrition of the intervertebral disc;Urban;Spine (Phila Pa 1976),2004

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