Dependence of the biological activity and mass spectrometric pattern on the structure peculiarities of the molecule of alkylating drug thiotepa
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Biochemistry,Biophysics
Reference28 articles.
1. Nucleic acid base complexes with thiotepa as revealed by field ionization mass spectrometry
2. Direct observation of the alkylation products of deoxyguanosine and DNA by fast atom bombardment mass spectrometry
3. Hydrolysis of 1,1˙,1″-phosphinothioylidinetrisaziridine (thiotepa) in aqueous solution
4. Fast atom bombardment mass spectra of thiotepa
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1. Chemical reactivity analysis of some alkylating drug molecules – A density functional theory approach;Computational and Theoretical Chemistry;2011-08
2. Some physicochemical properties of the antitumor drug thiotepa and its metabolite tepa as obtained by density functional theory (DFT) calculations;Journal of Molecular Modeling;2010-02-14
3. APPLICATIONS OF NUCLEAR MAGNETIC RESONANCE AND MASS SPECTROMETRY TO ANTICANCER DRUG DISCOVERY;Novel Anticancer Agents;2006
4. Electronic Structure of Thio-TEPA Antitumor Drug;The Journal of Organic Chemistry;1999-05-01
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