Bitter gourd seed fatty acid rich in 9c,11t,13t-conjugated linolenic acid induces apoptosis and up-regulates the GADD45, p53 and PPARγ in human colon cancer Caco-2 cells

Author:

Yasui Yumiko,Hosokawa Masashi,Sahara Takehiko,Suzuki Rikako,Ohgiya Satoru,Kohno Hiroyuki,Tanaka Takuji,Miyashita Kazuo

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry

Reference34 articles.

1. Protection of conjugated linoleic acids against 2-amino-3-methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms;Liew;Carcinogenesis,1995

2. Inhibition of benzo(a)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid;Ha;Cancer Res.,1990

3. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and β-carotene on the in vitro growth of human cancer cells;Shultz;Cancer Lett.,1992

4. The inhibitory effect of conjugated dienoic derivatives (CLA) of linoleic acid on the growth of human tumor cell lines is in part due to increased lipid peroxidation;Schφnberg;Anticancer Res.,1995

5. The growth inhibitory effect of conjugated linoleic acid on MCF-7 cells is related to estrogen response system;Durgam;Cancer Lett.,1997

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