Total neoadjuvant treatment and organ preservation strategies in the management of localized rectal cancer: A narrative review and evidence-based algorithm

Author:

Borelli Beatrice,Germani Marco Maria,Carullo Martina,Mattioni Roberto,Manfredi Bruno,Sainato Aldo,Rossi Piercarlo,Vagli Paola,Balestri Riccardo,Buccianti Piero,Morelli Luca,Antoniotti Carlotta,Cremolini Chiara,Masi Gianluca,Moretto Roberto

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference108 articles.

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2. Non-operative management after chemoradiotherapy plus consolidation or sandwich (induction with bevacizumab and consolidation) chemotherapy in patients with locally advanced rectal cancer: a multicentre, randomised phase II trial (NOMINATE trial;Akiyoshi;BMJ Open,2022

3. Alliance for Clinical Trials in Oncology, 2023. The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing The Efficacy of Triplet Versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients With Locally Advanced Rectal Cancer. clinicaltrials.gov; 2023.

4. Ambraziene R. , 2022. Evaluation and Comparison of the Efficacy of a New Standard Pre-operative Chemotherapy for Stage II and III Colorectal Cancer According to the FOLFOX4 Regimen With Routine Chemoradiation Therapy. clinicaltrials.gov; 2022.

5. Safety and efficacy of anti–PD-1 antibody dostarlimab in patients (pts) with mismatch repair-deficient (dMMR) solid cancers: Results from GARNET study;Andre;JCO,2021

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