Human aging is associated with stochastic somatic mutations of mitochondrial DNA

Author:

Kadenbach Bernhard,Münscher Christof,Frank Viola,Müller-Höcker Josef,Napiwotzki Jörg

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Ageing

Reference112 articles.

1. Sequence and organization of the human mitochondrial genome;Anderson;Nature,1981

2. Abnormal RNA processing associated with a novel tRNA mutation in mitochondrial DNA. A potential disease mechanism;Bindoff;J. Biol. Chem.,1993

3. Decline with age of the respiratory chain activity in human skeletal muscle;Boffoli;Biochim. Biophys. Acta,1994

4. Distribution and threshold expression of the tRNALys mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF);Boulet;Am. J. Hum. Genet.,1992

5. Fate and expression deleted mitochondrial DNA differ between human heteroplasmic skin fibroblast and Epstein-Barr virus-transformed lymphocyte cultures;Bourgeron;J. Biol. Chem.,1993

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