Endothelin-1 Across the Lung Circulation in Patients With Pulmonary Arterial Hypertension and Influence of Epoprostenol Infusion

Author:

Selimovic Nedim,Andersson Bert,Bergh Claes-Håkan,Sakiniene Egidija,Carlsten Hans,Rundqvist Bengt

Publisher

Elsevier BV

Subject

Transplantation,Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,Surgery

Reference31 articles.

1. Primary pulmonary hypertension;Rubin;N Engl J Med,1997

2. Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension;Lee;J Clin Invest,1998

3. The orally active ET (A) receptor antagonist (+)-(S)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphe nyl-propionic acid (LU 135252) prevents the development of pulmonary hypertension and endothelial metabolic dysfunction in monocrotaline-treated rats;Prie;J Pharmacol Exp Ther,1997

4. The orally active nonpeptide endothelin A-receptor antagonist A-127722 prevents and reverses hypoxia-induced pulmonary hypertension and pulmonary vascular remodeling in Sprague-Dawley rats;Chen;J Cardiovasc Pharmacol,1997

5. A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channels;Yanagisawa;J Hypertens Suppl,1988

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