Amphiphilic vehicles improve the oral bioavailability of a poorly soluble HIV protease inhibitor at high doses1Portions of this work were presented at Journeé Galéniques de Saint-Rémy de Provence, May 1994, and at the AAPS Eastern Regional Meeting, June 1994.1-Reference-Cited by-同舟云学术

Amphiphilic vehicles improve the oral bioavailability of a poorly soluble HIV protease inhibitor at high doses1Portions of this work were presented at Journeé Galéniques de Saint-Rémy de Provence, May 1994, and at the AAPS Eastern Regional Meeting, June 1994.1

Published:1997-10 Issue:1 Volume:156 Page:79-88
ISSN:0378-5173
Container-title:International Journal of Pharmaceutics
language:en
Short-container-title:International Journal of Pharmaceutics

Author:

Aungst Bruce J,Nguyen Nhung H,Rogers Nancy J,Rowe Susan M,Hussain Munir A,White Susan J,Shum Linyee

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference9 articles.

1. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors;Condra;Nature,1995

2. Absorption potential: estimating the fraction absorbed for orally administered compounds;Dressman;J. Pharm. Sci.,1985

3. The current status of solid dispersions;Ford;Pharm. Acta Helv.,1986

4. Pharmacokinetics of HIV protease inhibitor DMP 323 in rats and dogs;Grubb;Drug Metab. Disp.,1994

5. Safety and activity of saquinavir in HIV infection;Kitchen;Lancet,1995

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