Permeability of lipophilic compounds in drug discovery using in-vitro human absorption model, Caco-2

Author:

Krishna Gopal,Chen Kwang-jong,Lin Chin-chung,Nomeir Amin A

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference18 articles.

1. Caco-2 monolayers in experimental and theoretical predictions of drug transport;Artursson;Adv. Drug Del. Rev.,1996

2. Evidence of a polarized efflux system in Caco-2 cells capable of modulating cyclosporine A transport;Augustinjns;Biochem. Biophys. Res. Commun.,1993

3. The use of the intestinal epithelial cell culture model, Caco-2, in pharmaceutical development;Bailey;Adv. Drug Del. Rev.,1996

4. Pharmacokinetics and mechanisms of drug absorption in drug discovery, preclinical and Phase I studies;Barr,1996

5. Absorption of Cam-2445, an NK1 neurokinin receptor antagonist: in vivo, in situ, and in vitro evaluations;Chan;J. Pharm. Sci.,1996

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