Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice

Author:

Afouna Mohsen I,Fincher Timothy K,Zaghloul Abdel-Azim A,Reddy Indra K

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference22 articles.

1. Metabolism diversity and antiviral activities of acyclic nucleoside phosphonates;Aduma;Mol. Pharmacol.,1995

2. Influence of various azone concentrations upon the permeability parameters for acyclovir (ACV) and (E)-5-(2-bromovinyl)-2-deoxyuridine (BVDU) topical formulations using hairless mice: a comparative study;Afouna;Az. J. Pharm. Sci.,2001

3. Assessment of correlation between skin target site free drug concentration and the in vivo topical antiviral efficacy in hairless mice for (E)-5-(2-bromovinyl)-2-deoxyuridine and acyclovir formulations;Afouna;J. Pharm. Sci.,1998

4. Influence of the treatment protocol upon the in vivo efficacy of cidofovir (HPMPC) and of acyclovir (ACV) formulations in topical treatment of cutaneous HSV-1 infection in hairless mice;Afouna;J. Pharm. Sci.,1999

5. Metabolism of ((S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in human embryonic lung cells;Cihlar;Coll. Czech. Chem. Commun.,1992

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