CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair

Author:

Ström Cecilia E.,Mortusewicz Oliver,Finch David,Parsons Jason L.,Lagerqvist Anne,Johansson Fredrik,Schultz Niklas,Erixon Klaus,Dianov Grigory L.,Helleday Thomas

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference49 articles.

1. Instability and decay of the primary structure of DNA;Lindahl;Nature,1993

2. Poly(ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate;Strom;Nucleic Acids Res.,2010

3. Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines;Singer;Proc. Natl. Acad. Sci. U.S.A.,1981

4. Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3′-phosphate and 3′-phosphoglycolate ends;Takahashi;Nucleic Acids Res.,2007

5. APE1 is the major 3′-phosphoglycolate activity in human cell extracts;Parsons;Nucleic Acids Res.,2004

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