Increase in expression of the GABAA receptor α4 subunit gene induced by withdrawal of, but not by long-term treatment with, benzodiazepine full or partial agonists

Author:

Follesa Paolo,Cagetti Elisabetta,Mancuso Luisa,Biggio Francesca,Manca Annalisa,Maciocco Elisabetta,Massa Federico,Speranza Desole Maria,Carta Mario,Busonero Fabio,Sanna Enrico,Biggio Giovanni

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Molecular Biology

Reference54 articles.

1. Imidazenil, a partial positive allosteric modulator of GABAA receptors, exhibits low tolerance and dependence liabilities in the rat;Auta;J. Pharmacol. Exp. Ther.,1994

2. Imidazenil prevention of alprazolam-induced acquisition deficit in patas monkeys is devoid of tolerance;Auta;Proc. Natl. Acad. Sci. USA,2000

3. International Union of Pharmacology. XV. Subtypes of γ-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function;Barnard;Pharmacol. Rev.,1998

4. A significant part of native γ-aminobutyric acidA receptors containing α4 subunits do not contain γ or δ subunits;Bencsits;J. Biol. Chem.,1999

5. Expression patterns of γ-aminobutyric acid type A receptor subunit mRNAs in primary cultures of granule neurons and astrocytes from neonatal rat cerebella;Bovolin;Proc. Natl. Acad. Sci. USA,1992

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