Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis

Author:

Zhang Kevin R.ORCID,Baumann Bailey,Song Ying,Sterling Jacob,Erler Elizabeth A.,Guttha Samyuktha,Kozmik Zbynek,Dunaief Joshua L.

Funder

NIH

National Eye Institute

Research to Prevent Blindness

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Reference29 articles.

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2. Ocular siderosis: a misdiagnosed cause of visual loss due to ferrous intraocular foreign bodies—epidemiology, pathogenesis, clinical signs, imaging and available treatment options;Casini;Doc. Ophthalmol.,2020

3. Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI-ceruloplasmin;Domenico;EMBO J.,2007

4. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis;Donovan;Cell Metabol.,2005

5. Macular degeneration in a patient with aceruloplasminemia, a disease associated with retinal iron overload;Dunaief;Ophthalmology,2005

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