Declines in PDE4B activity promote myopia progression through downregulation of scleral collagen expression

Author:

Zhao FuxinORCID,Zhou Hui,Chen WeiORCID,Zhao Chenchen,Zheng Yangyang,Tao Yijin,Pan Miaozhen,Reinach Peter S.ORCID,Zhu Jiadi,An Jianhong,Lu Runxia,Chen Jiang-fan,Tang Huifang,Zeng Changqing,Qu Jia,Zhou XiangtianORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Chinese Academy of Medical Sciences

National Key Research and Development Program of China

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Reference42 articles.

1. Myopia;Baird;Nat Rev Dis Primers,2020

2. Variational analysis of the mouse and rat eye optical parameters;Bawa;Biomed. Opt Express,2013

3. Scleral structure and biomechanics;Boote;Prog. Retin. Eye Res.,2020

4. Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition;Cai;Biochim. Biophys. Acta Mol. Cell Res.,2018

5. Comparison of refractive development and retinal dopamine in OFF pathway mutant and C57BL/6J wild-type mice;Chakraborty;Mol. Vis.,2014

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