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Evidence that cannabinoid CB1 receptors regulate intraocular pressure via two opposing mechanisms

  • Published:2020-11 Issue: Volume:200 Page:108241
  • ISSN:0014-4835
  • Container-title:Experimental Eye Research
  • language:en
  • Short-container-title:Experimental Eye Research

Author:

Miller Sally,Daily Laura,Ploss Maya,Greig Iain,Ross Ruth,Rayana Naga Pradeep,Dai Jiannong,Sugali Chenna Kesavulu,Mao Weiming,Straiker Alex

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Reference28 articles.

1. Pharmacology of the intraocular pressure (IOP) lowering effect of systemic dexanabinol (HU-211), a non-psychotropic cannabinoid;Beilin;J. Ocul. Pharmacol. Therapeut.,2000

2. The in vivo effects of the CB1-positive allosteric modulator GAT229 on intraocular pressure in ocular normotensive and hypertensive mice;Cairns;J. Ocul. Pharmacol. Therapeut.,2017

3. A GPR18-based signaling system regulates IOP in murine eye;Caldwell;Br. J. Pharmacol.,2013

4. TGFbeta2-induced changes in human trabecular meshwork: implications for intraocular pressure;Fleenor;Invest. Ophthalmol. Vis. Sci.,2006

5. Interaction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye;Green;Invest. Ophthalmol.,1976
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