Deep phenotyping of the Cdhr1 mouse validates its use in pre-clinical studies for human CDHR1-associated retinal degeneration

Author:

Yusuf Imran H.,McClements Michelle E.ORCID,MacLaren Robert E.,Charbel Issa Peter

Funder

National Institute for Health Research

Medical Research Council

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Reference33 articles.

1. A clinical study of patients with novel CDHR1 genotypes associated with late-onset macular dystrophy;Ba-Abbad;Eye,2020

2. Clinical characteristics of early retinal disease due to CDHR1 mutation;Ba-Abbad;Mol. Vis.,2013

3. Clinical characteristics of recessive retinal degeneration due to mutations in the CDHR1 gene and a review of the literature CDHR1 mutations in retinal dystrophies;Bessette;Ophthalmic Genet.,2017

4. Rod disc renewal occurs by evagination of the ciliary plasma membrane that makes cadherin-based contacts with the inner segment;Burgoyne;Proc. Natl. Acad. Sci. U. S. A.,2015

5. Distinct roles for prominin-1 and photoreceptor cadherin in outer segment disc morphogenesis in CRISPR-altered X. laevis;Carr;J. Cell Sci.,2021

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