The homeobox gene Otx2 in development and disease

Author:

Beby Francis,Lamonerie Thomas

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Reference49 articles.

1. Forebrain and midbrain regions are deleted in Otx2−/− mutants due to a defective anterior neuroectoderm specification during gastrulation;Acampora;Development,1995

2. Otx2 homeobox gene induces photoreceptor-specific phenotypes in cells derived from adult iris and ciliary tissue;Akagi;Invest. Ophthalmol. Vis. Sci.,2004

3. A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain;Ang;Development,1996

4. A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency;Ashkenazi-Hoffnung;Hum. Genet.,2010

5. OTX2 represses myogenic and neuronal differentiation in medulloblastoma cells;Bai;Cancer Res.,2012

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