Miniaturization of Mass Spectrometry Analysis Systems-Reference-Cited by-同舟云学术

Miniaturization of Mass Spectrometry Analysis Systems

Published:2010-12 Issue:6 Volume:15 Page:433-439
ISSN:1535-5535
Container-title:JALA: Journal of the Association for Laboratory Automation
language:en
Short-container-title:JALA: Journal of the Association for Laboratory Automation

Author:

Xu Wei¹,Manicke Nicholas E.²,Cooks Graham R.²,Ouyang Zheng¹

Affiliation:

1. Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN

2. Department of Chemistry, Purdue University, West Lafayette, IN

Abstract

The key concepts and technologies developed in our laboratories in Purdue University for the miniaturization of mass spectrometry analysis systems are introduced. Mass analyzers of simple geometries with a novel atmospheric pressure interface were used to allow reduction in the size of the ion trap mass spectrometer. Ambient ionization methods were developed and coupled to miniature mass spectrometers to allow direct MS analysis of complex samples without sample preparation and chemical separation. The performance of desorption electrospray ionization, low temperature plasma probe, paper spray, and two handheld MS systems, Mini 10 and Mini 11, are described with demonstrations of capabilities for chemical analysis.

Publisher

SAGE Publications

Subject

Medical Laboratory Technology,Computer Science Applications

Link

http://journals.sagepub.com/doi/pdf/10.1016/j.jala.2010.06.004

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