A Compound L1196M/G1202R ALK Mutation in a Patient with ALK-Positive Lung Cancer with Acquired Resistance to Brigatinib Also Confers Primary Resistance to Lorlatinib
Author:
Funder
European Union
Italian Association for Cancer Research
Publisher
Elsevier BV
Subject
Pulmonary and Respiratory Medicine,Oncology
Reference5 articles.
1. ALK in lung cancer: past, present, and future;Shaw;J Clin Oncol,2013
2. Molecular mechanisms of resistance to first- and second-generation ALK inhibitors in ALK-rearranged lung cancer;Gainor;Cancer Discov,2016
3. Clinical utility of cell-free DNA for the detection of ALK fusions and genomic mechanisms of ALK inhibitor resistance in non-small cell lung cancer;McCoach;Clin Cancer Res,2018
4. Brigatinib versus crizotinib in ALK-positive non-small-cell lung cancer;Camidge;N Engl J Med,2018
5. Sequential ALK inhibitors can select for lorlatinib-resistant compound ALK mutations in ALK-positive lung cancer;Yoda;Cancer Discov,2018
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