Novel 2-D phosphorene-based drug delivery system for anti-HIV zidovudine drug to enhance the therapeutic effects: A first-principles based study

Author:

Ullah Sami,Akram Waqas,Mahmood Muhammad Saad,Shazad Nabeel,Zahid Muhammad Nauman,Iqbal JavedORCID

Publisher

Elsevier BV

Subject

Physical and Theoretical Chemistry,Condensed Matter Physics,Biochemistry

Reference73 articles.

1. Study on experimental and theoretical vibrational spectra of novel anti AIDS drug: Zidovudine-iron metal complex derived from 3′-Azido-2′-deoxythymidine;Singh;Asian J. Spectros,2010

2. HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment;Saylor;Nat. Rev. Neurol.,2016

3. Enhanced brain delivery of an anti-HIV nucleoside 2′-F-ara-ddI by xanthine oxidase mediated biotransformation;Shanmuganathan;J. Med. Chem.,1994

4. Structure and conformational analysis of the anti-HIV reverse transcriptase inhibitor AZT using MP2 and DFT methods. Differences with the natural nucleoside thymidine. Simulation of the 1st phosphorylation step with ATP;Palafox;PCCP,2014

5. Food, U., Drug Administration, 2015, http://www.fda.gov.FDAC/features/2000/100_online.html.

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