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Fingolimod (FTY720) prevents chronic rejection of rodent cardiac allografts through inhibition of the RhoA pathway

  • Published:2021-04 Issue: Volume:65 Page:101347
  • ISSN:0966-3274
  • Container-title:Transplant Immunology
  • language:en
  • Short-container-title:Transplant Immunology

Author:

Chen Wei,Chen Wenhao,Chen Song,Uosef Ahmed,Ghobrial Rafik M.,Kloc Malgorzata

Funder

Novartis

William Stamps Farish Fund

Publisher

Elsevier BV

Subject

Transplantation,Immunology,Immunology and Allergy

Reference29 articles.

1. Ghobrial RM Macrophage/monocyte-specific deletion of RhoA down-regulates fractalkine receptor and inhibits chronic rejection of mouse cardiac allografts;Liu;J. Heart Lung Transplant.,2017

2. Coinhibition of mTORC1/mTORC2 and RhoA/ROCK pathways prevents chronic rejection of rat cardiac allografts;Chen;Transpl. Rep.,2018

3. Screening RhoA/ROCK inhibitors for the ability to prevent chronic rejection of mouse cardiac allografts;Chen;Transpl. Immunol.,2018

4. ROCK1 inhibitor abrogates chronic rejection in rat cardiac model system;Zhang;Open J Organ Transp Surg.,2012

5. ROCK1 inhibitor abrogates chronic rejection in rat cardiac model system;Zhang;Open J. Organ Transpl. Surg.,2012

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