Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease

Author:

Vounou Maria,Janousova Eva,Wolz Robin,Stein Jason L.,Thompson Paul M.,Rueckert Daniel,Montana Giovanni

Funder

EPSRC

GlaxoSmithKline Clinical Imaging Center

European Union 7th Framework Program, PredictAD, From Patient Data to Personalised Healthcare in Alzheimer's Disease

National Institutes of Health

National Institute on Aging

National Institute of Biomedical Imaging and Bioengineering

Abbott

AstraZeneca AB

Bayer Schering Pharma AG

Bristol-Myers Squibb

Eisai Global Clinical Development

Elan Corporation

Genentech

GE Healthcare

GlaxoSmithKline

Innogenetics

Johnson and Johnson

Eli Lilly and Co.

Medpace, Inc.

Merck and Co., Inc.

Novartis AG

Pfizer Inc

F. Hoffman-La Roche

Schering-Plough

Synarc, Inc.

Wyeth

Alzheimer's Association and Alzheimer's Drug Discovery Foundation

U.S. Food and Drug Administration

Northern California Institute for Research and Education

Publisher

Elsevier BV

Subject

Cognitive Neuroscience,Neurology

Reference103 articles.

1. Alzheimer's disease facts and figures;Alzheimer's Dement.,2011

2. Structural magnetic resonance imaging in established and prodromal Alzheimer disease: a review;Atiya;Alzheimer Dis. Assoc. Disord.,2003

3. APOE, ACT and CHRNA7 genes in the conversion from amnestic mild cognitive impairment to Alzheimer's disease;Barabash;Neurobiol. Aging,2009

4. A general and unifying framework for feature construction, in image-based pattern classification;Batmanghelich,2009

5. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder;Baum;Mol. Psychiatry,2008

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