A formalized safety system for closed-loop anesthesia with pharmacokinetic and pharmacodynamic constraints

Author:

Yousefi Mahdi,van Heusden Klaske,West Nicholas,Mitchell Ian M.,Ansermino J. Mark,Dumont Guy A.

Funder

NSERC/CIHR Collaborative Health Research Projects

Publisher

Elsevier BV

Subject

Applied Mathematics,Electrical and Electronic Engineering,Computer Science Applications,Control and Systems Engineering

Reference38 articles.

1. Agrawal, G., Bibian, S., & Zikov, T. (2010). Recommended clinical range for wavcns index during general anesthesia. In Proceedings of the 2010 annual meeting of the American society of anesthesiologists.

2. Viability theory: New directions;Aubin,2011

3. Impact of a preoperative conversational hypnotic session on propofol consumption using closed-loop anesthetic induction guided by the bispectral index: a randomized controlled trial;Bataille;Medicine,2017

4. Bibian, S., Dumont, G. A., Huzmezan, M., & Ries, C. R. (2006). Patient variability and uncertainty quantification in clinical anesthesia: Part I–PKPD modeling and identification. In IFAC symposium on modelling and control in biomedical systems, Reims, France.

5. Clinical performance and safety of closed-loop systems: A systematic review and meta-analysis of randomized controlled trials;Brogi;Anesthesia and Analgesia,2017

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