Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain-Reference-Cited by-同舟云学术

Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain

Published:2014-09 Issue: Volume:87 Page:87-93
ISSN:1043-6618
Container-title:Pharmacological Research
language:en
Short-container-title:Pharmacological Research

Author:

Moreno-Sanz Guillermo,Barrera Borja,Armirotti Andrea,Bertozzi Sine M.,Scarpelli Rita,Bandiera Tiziano,Prieto Julio G.,Duranti Andrea,Tarzia Giorgio,Merino Gracia,Piomelli Daniele

Publisher

Elsevier BV

Subject

Pharmacology

Reference31 articles.

1. Modelling of the blood–brain barrier in drug discovery and development;Cecchelli;Nat Rev Drug Discov,2007

2. Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up;Agarwal;Curr Pharm Des,2011

3. Human ABC transporters at blood–CNS interfaces as determinants of CNS drug penetration;Chaves;Curr Pharm Des,2014

4. Transporters and drug–drug interactions: important determinants of drug disposition and effects;Konig;Pharmacol Rev,2013

5. ABC multidrug transporters: structure, function and role in chemoresistance;Sharom;Pharmacogenomics,2008

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