Cinnamtannin D1 attenuates autoimmune arthritis by regulating the balance of Th17 and treg cells through inhibition of aryl hydrocarbon receptor expression

Author:

Shi Chenchen,Zhang Haoyue,Wang Xiaoyu,Jin Bingliang,Jia Qi,Li Yiming,Yang Yifu

Funder

Natural Science Foundation of Shanghai

National Natural Science Foundation of China

Excellent Academic Leaders Program of Shanghai

Shanghai Municipality High Institutions First-Class Discipline Innovation Fund of Traditional Chinese Medicine

Shanghai E-Research Institute of Bioactive Constituent in TCM” Plan

Xinlin Young Talent Program

Publisher

Elsevier BV

Subject

Pharmacology

Reference44 articles.

1. Collagen antibody-induced arthritis: A Disease-Relevant Model for Studies of Persistent Joint Pain;Sandor,2012

2. Novel therapeutic targets in rheumatoid arthritis;Koenders;Trends Pharmacol. Sci.,2015

3. The role of the immune system in metabolic health and disease;Zmora;Cell Metab.,2017

4. Th17 and regulatory T cell balance in autoimmune and inflammatory diseases;Noack;Autoimmun. Rev.,2014

5. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist;Nakae;Proc Natl Acad Sci U S A,2003

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