Activation of PKM2 metabolically controls fulminant liver injury via restoration of pyruvate and reactivation of CDK1-Reference-Cited by-同舟云学术

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Activation of PKM2 metabolically controls fulminant liver injury via restoration of pyruvate and reactivation of CDK1

Published:2021-10 Issue: Volume:172 Page:105838
ISSN:1043-6618
Container-title:Pharmacological Research
language:en
Short-container-title:Pharmacological Research

Author:

Lv Xiaohui,Zhou Honghong,Hu Kai,Lin Ling,Yang Yongqiang,Li Longjiang,Tang Li,Huang Jiayi,Shen Yi,Jiang Rong,Wan Jingyuan,Zhang Li

Funder

National Natural Science Foundation of China

Chongqing Municipal Education Commission

Publisher

Elsevier BV

Subject

Pharmacology

Reference46 articles.

1. Apoptosis and necroptosis in the liver: a matter of life and death;Schwabe;Nat. Rev. Gastroenterol. Hepatol.,2018

2. To die or not to die: death signaling in nonalcoholic fatty liver disease;Akazawa;J. Gastroenterol.,2018

3. Targeting metabolic pathways for extension of lifespan and healthspan across multiple species;Parkhitko;Ageing Res. Rev.,2020

4. Targeting metabolic dysregulation for fibrosis therapy;Zhao;Nat. Rev. Drug Discov.,2020

5. Glycolysis - a key player in the inflammatory response;Soto-Heredero;FEBS J.,2020

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tetramerization of PKM2 Alleviates Traumatic Brain Injury by Ameliorating Mitochondrial Damage in Microglia;Journal of Neuroimmune Pharmacology;2024-08-28

2. Distinct signatures of gut microbiota and metabolites in primary biliary cholangitis with poor biochemical response after ursodeoxycholic acid treatment;Cell & Bioscience;2024-06-15

3. Design, synthesis, and biological evaluation of novel sesquiterpene lactone derivatives as PKM2 activators with potent anti-ulcerative colitis activities;European Journal of Medicinal Chemistry;2024-06

4. Salvia miltiorrhiza polysaccharide mitigates AFB1-induced liver injury in rabbits;Ecotoxicology and Environmental Safety;2024-05

5. Pyruvate kinase M2 regulates mitochondrial homeostasis in cisplatin-induced acute kidney injury;Cell Death & Disease;2023-10-10

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