The PI3Kα inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation-Reference-Cited by-同舟云学术

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The PI3Kα inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation

Published:2020-10 Issue: Volume:160 Page:105147
ISSN:1043-6618
Container-title:Pharmacological Research
language:en
Short-container-title:Pharmacological Research

Author:

Fan Yan-Hua,Ding Huai-Wei,Kim Donghwa,Liu Jian-Yu,Hong Ji-Young,Xu Yong-Nan,Wang Daoping,Yang Xiao-Sheng,Lee Sang Kook

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guizhou Province, China

Science and Technology Foundation of Guiyang, Guizhou Province, China

Publisher

Elsevier BV

Subject

Pharmacology

Reference38 articles.

1. Loss of EphB6 expression in metastatic melanoma;Hafner;Int. J. Oncol.,2003

2. LncRNA DGCR5 regulates the non-small cell lung cancer cell growth, migration, and invasion through regulating miR-211-5p/EPHB6 axis;Kang;Biofactors,2019

3. The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer;Yu;Clin. Cancer Res.,2010

4. Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer;Muller-Tidow;Cancer Res.,2005

5. EphB receptors trigger akt activation and suppress fas receptor-induced apoptosis in malignant T lymphocytes;Maddigan;J. Immunol.,2011

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