Tubocapsenolide A targets C-terminal cysteine residues of HSP90 to exert the anti-tumor effect
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Pharmacology
Reference44 articles.
1. Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress;Workman;Ann. N. Y. Acad. Sci.,2007
2. HSP90 molecular chaperone inhibitors: are we there yet?;Neckers;Clin. Cancer Res.,2012
3. The HSP90chaperone machinery;Schopf;Nat. Rev. Mol. Cell Biol.,2017
4. A nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of HSP90. N-terminal nucleotide binding unmasks a C-terminal binding pocket;Söti;J. Biol. Chem.,2002
5. Deguelin analogue SH-1242 inhibits HSP90 activity and exerts potent anticancer efficacy with limited neurotoxicity;Lee;Cancer Res.,2016
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Allosteric site identification, virtual screening and discovery of a sulfonamide Hsp110-STAT3 interaction inhibitor for the treatment of hypoxic pulmonary arterial hypertension;European Journal of Medicinal Chemistry;2024-12
2. Ultrasound-assisted extraction of withanolides from Tubocapsicum anomalum: Process optimization, isolation and identification, and antiproliferative activity;Ultrasonics Sonochemistry;2024-11
3. Targeting HSP90 for Cancer Therapy: Current Progress and Emerging Prospects;Journal of Medicinal Chemistry;2024-09-10
4. Heat shock proteins as hallmarks of cancer: insights from molecular mechanisms to therapeutic strategies;Journal of Hematology & Oncology;2024-09-04
5. Covalent binding of withanolides to cysteines of protein targets;Biochemical Pharmacology;2024-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3