A novel quantitative assay of mitophagy: Combining high content fluorescence microscopy and mitochondrial DNA load to quantify mitophagy and identify novel pharmacological tools against pathogenic heteroplasmic mtDNA
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Published:2015-10
Issue:
Volume:100
Page:24-35
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ISSN:1043-6618
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Container-title:Pharmacological Research
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language:en
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Short-container-title:Pharmacological Research
Author:
Diot AlanORCID,
Hinks-Roberts AlexORCID,
Lodge Tiffany,
Liao Chunyan,
Dombi Eszter,
Morten Karl,
Brady Stefen,
Fratter CarlORCID,
Carver Janet,
Muir Rebecca,
Davis RyanORCID,
Green Charlotte J,
Johnston Iain,
Hilton-Jones David,
Sue Carolyn,
Mortiboys Heather,
Poulton Joanna
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4. LC3, a mammalian homologue of yeast Apg, is localized in autophagosome membranes after processing;Kabeya;EMBO J.,2000
5. Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation;Kim;Am. J. Physiol. Cell Physiol.,2011
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