Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition
Author:
Funder
NIH
Publisher
Elsevier BV
Subject
Pharmacology
Reference89 articles.
1. A novel transforming protein (shc) with an sh2 domain is implicated in mitogenic signal transduction;Pelicci;Cell,1992
2. Phosphotyrosine-dependent interaction of shc and insulin receptor substrate 1 with the npey motif of the insulin receptor via a novel non-sh2 domain;Gustafson;Molecular and cellular biology,1995
3. Ptb domains of irs-1 and shc have distinct but overlapping binding specificities;Wolf;The Journal of biological chemistry,1995
4. The shc locus regulates insulin signaling and adiposity in mammals;Tomilov;Aging cell,2011
5. Influence of obesity and insulin sensitivity on insulin signaling genes in human omental and subcutaneous adipose tissue;MacLaren;Journal of lipid research,2008
Cited by 19 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy;Cell Reports Medicine;2024-01
2. When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging;Cell Metabolism;2023-07
3. Coenzyme Q-related compounds to maintain healthy mitochondria during aging;Advances in Protein Chemistry and Structural Biology;2023
4. Shc Is Implicated in Calreticulin-Mediated Sterile Inflammation in Alcoholic Hepatitis;Cellular and Molecular Gastroenterology and Hepatology;2023
5. Mitochondria-targeted antioxidants: coenzyme Q10, mito-Q and beyond;Molecular Nutrition and Mitochondria;2023
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3