Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
Author:
Funder
Leukemia and Lymphoma Society
NIA
American Society of Hematology
NICHD
Ellison Medical Foundation
NCI
NIDDK
Publisher
Elsevier BV
Subject
Cell Biology,Genetics,Molecular Medicine
Reference59 articles.
1. Aging human hematopoietic stem cells manifest profound epigenetic reprogramming of enhancers that may predispose to leukemia;Adelman;Cancer Discov.,2019
2. Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization;Baccin;Nat. Cell Biol.,2020
3. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion;Beerman;Proc. Natl. Acad. Sci. U S A,2010
4. The majority of cd45(-) ter119(-) cd31(-) bone marrow cell fraction is of hematopoietic origin and contains erythroid and lymphoid progenitors;Boulais;Immunity,2018
5. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position;Buenrostro;Nat. Methods,2013
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