Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease

Author:

Warren Curtis R.,O’Sullivan John F.,Friesen Max,Becker Caroline E.,Zhang Xiaoling,Liu Poching,Wakabayashi Yoshiyuki,Morningstar Jordan E.,Shi Xu,Choi Jihoon,Xia Fang,Peters Derek T.,Florido Mary H.C.,Tsankov Alexander M.,Duberow Eilene,Comisar Lauren,Shay Jennifer,Jiang Xin,Meissner Alexander,Musunuru Kiran,Kathiresan Sekar,Daheron Laurence,Zhu Jun,Gerszten Robert E.,Deo Rahul C.,Vasan Ramachandran S.,O’Donnell Christopher J.,Cowan Chad A.

Funder

NIH/NHLBI

NIH/NIDDDK

Harvard University

Harvard Stem Cell Institute

National Heart Lung and Blood Institute

NIH

NHLBI Framingham Heart Study

Publisher

Elsevier BV

Subject

Cell Biology,Genetics,Molecular Medicine

Reference41 articles.

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3. Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing;Benjamini;J. R. Stat. Soc. Ser. A Stat. Soc.,1995

4. Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines;Bock;Cell,2011

5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population;Comuzzie;PLoS ONE,2012

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