NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia-Reference-Cited by-同舟云学术

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NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia

Published:2019-11 Issue:5 Volume:25 Page:607-621.e7
ISSN:1934-5909
Container-title:Cell Stem Cell
language:en
Short-container-title:Cell Stem Cell

Author:

Román-Rodríguez Francisco José,Ugalde Laura,Álvarez Lara,Díez Begoña,Ramírez María José,Risueño Cristina,Cortón Marta,Bogliolo Massimo,Bernal Sara,March Francesca,Ayuso Carmen,Hanenberg Helmut,Sevilla Julián,Rodríguez-Perales Sandra,Torres-Ruiz Raúl,Surrallés Jordi,Bueren Juan Antonio,Río Paula

Funder

Ministerio de Economía, Comercio y Competitividad y Fondo Europeo de Desarrollo Regional

7th Framework Program European Commission

Ministerio de Sanidad, Servicios Sociales e Igualdad

Fondo de Investigaciones Sanitarias, Instituto de Salud Carlos III

ICREA-Academia program

Rocket Pharmaceuticals Inc.

Asociación Española Contra el Cáncer

Publisher

Elsevier BV

Subject

Cell Biology,Genetics,Molecular Medicine

Reference45 articles.

1. Somatic mosaicism of an intragenic FANCB duplication in both fibroblast and peripheral blood cells observed in a Fanconi anemia patient leads to milder phenotype;Asur;Mol. Genet. Genomic Med.,2018

2. In vitro micronucleus scoring by flow cytometry: differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability;Avlasevich;Environ. Mol. Mutagen.,2006

3. CRISPR/Cas9 genome editing in human hematopoietic stem cells;Bak;Nat. Protoc.,2018

4. Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9;Brunetti;J. Vis. Exp.,2018

5. A common founder mutation in FANCA underlies the world’s highest prevalence of Fanconi anemia in Gypsy families from Spain;Callén;Blood,2005

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