Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson’s Disease

Author:

Sommer Annika,Marxreiter Franz,Krach Florian,Fadler Tanja,Grosch Janina,Maroni Michele,Graef Daniela,Eberhardt Esther,Riemenschneider Markus J.,Yeo Gene W.,Kohl Zacharias,Xiang Wei,Gage Fred H.,Winkler Jürgen,Prots Iryna,Winner Beate

Funder

Bavarian Ministry of Education and Culture, Science, and the Arts

German Federal Ministry of Education and Research

BMBF

DFG funded research training group

DFG

Interdisciplinary Centre for Clinical Research

University Hospital of Erlangen

Bavarian Ministry of Education and Culture, Science and the Arts

JPB Foundation

Mathers Foundation

Lookout Foundation

Bavaria California Technology Center

BaCaTec

Publisher

Elsevier BV

Subject

Cell Biology,Genetics,Molecular Medicine

Reference38 articles.

1. Pluripotent stem cells in disease modelling and drug discovery;Avior;Nat. Rev. Mol. Cell Biol.,2016

2. Alterations of T-lymphocyte populations in Parkinson disease;Baba;Parkinsonism Relat. Disord.,2005

3. Lymphocyte populations in Parkinson’s disease and in rat models of parkinsonism;Bas;J. Neuroimmunol.,2001

4. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects;Borgs;Sci. Rep.,2016

5. Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease;Brochard;J. Clin. Invest.,2009

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