An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity

Author:

Hope Kristin J.,Cellot Sonia,Ting Stephen B.,MacRae Tara,Mayotte Nadine,Iscove Norman N.,Sauvageau Guy

Publisher

Elsevier BV

Subject

Cell Biology,Genetics,Molecular Medicine

Reference51 articles.

1. Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity;Adolfsson;Immunity,2001

2. A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23);Barbouti;Cancer Res.,2003

3. Asymmetric cell division within the human hematopoietic stem and progenitor cell compartment: Identification of asymmetrically segregating proteins;Beckmann;Blood,2007

4. Hematopoietic stem cells engraft in mice with absolute efficiency;Benveniste;Nat. Immunol.,2003

5. Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential;Benveniste;Cell Stem Cell,2010

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