Interaction between common folate polymorphisms and B-vitamin nutritional status modulates homocysteine and risk for a thrombotic event

Author:

Yates Zoe,Lucock Mark

Publisher

Elsevier BV

Subject

Endocrinology,Genetics,Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference35 articles.

1. Folic acid: nutritional biochemistry, molecular biology and role in disease processes;Lucock;Mol. Genet. Metab.,2001

2. Cobalamin-dependent methyltransferases;Matthews;Acc. Chem. Res.,2001

3. Human methionine synthase reductase, a soluble P-450 reductase-like dual flavoprotein, is sufficient for NADPH-dependent methionine synthase activation;Oteanu;J. Biol. Chem.,2001

4. Methionine synthase polymorphism A2756G is associated with susceptibility for thromboembolic events and altered B vitamin/thiol metabolism;Yates;Haematologica,2002

5. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase;Frosst;Nat. Genet.,1995

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