Contextualized genome-scale model unveils high-order metabolic effects of the specific growth rate and oxygenation level in recombinant Pichia pastoris-Reference-Cited by-同舟云学术

Contextualized genome-scale model unveils high-order metabolic effects of the specific growth rate and oxygenation level in recombinant Pichia pastoris

Published:2019-12 Issue: Volume:9 Page:e00103
ISSN:2214-0301
Container-title:Metabolic Engineering Communications
language:en
Short-container-title:Metabolic Engineering Communications

Author:

Torres Paulina,Saa Pedro A.,Albiol Joan,Ferrer Pau,Agosin Eduardo

Funder

CORFO

MINECO

FEDER

Doctoral National Program

CONICYT

Reference Network in Biotechnology

Generalitat de Catalunya

Publisher

Elsevier BV

Subject

Biomedical Engineering,Endocrinology, Diabetes and Metabolism

Reference66 articles.

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2. A multi-level study of recombinant Pichia pastoris in different oxygen conditions;Baumann;BMC Syst. Biol.,2010

3. Hypoxic fed-batch cultivation of Pichia pastoris increases specific and volumetric productivity of recombinant proteins;Baumann;Biotechnol. Bioeng.,2008

4. Reverse engineering of protein secretion by uncoupling of cell cycle phases from growth;Buchetics;Biotechnol. Bioeng.,2011

5. Recombinant protein production in Pichia pastoris under glyceraldehyde-3-phosphate dehydrogenase promoter: from carbon source metabolism to bioreactor operation parameters;Calik;Biochem. Eng. J.,2015

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