Prevalence of Risk Factors for Contrast-Induced Nephrotoxicity in Outpatients Undergoing Intravenous Contrast-Enhanced Computed Tomography Studies

Author:

Carstensen Michael1,Keer Dipinder2,Rempel Jeremy3,Jeon Paul4,Barrett Brendan5

Affiliation:

1. Department of Medical Imaging, St Joseph's Hospital, London, Ontario, Canada

2. Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada

3. Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada

4. Department of Radiology, Memorial University of Newfoundland, Health Sciences Centre, St John's, Newfoundland, Canada

5. Department of Nephrology, Memorial University of Newfoundland, Health Sciences Centre, St John's, Newfoundland, Canada

Abstract

Objective To document the prevalence and pattern of risk factors for contrast-induced nephrotoxicity (CIN) in an outpatient population referred for contrast-enhanced computed tomography (CT) (CECT) studies. Methods Over a 4-month period, 3261 patients presenting for CT studies were asked to consent to a survey of CIN risk factors. Among these patients, 957 were outpatients who received contrast material before the CT study. Demographic information and available serum creatinine (SCr) data for these patients were extracted from medical records and then analysed. A telephone questionnaire to document risk factors was administered to 200 of these patients, who were outpatients not referred from the emergency department or on dialysis. Results Among the 200 surveyed patients, 69% reported risk factors for CIN or for kidney function impairment (low estimated glomerular filtration rate [eGFR]) at baseline. Among these patients, 43% reported multiple (2 or more) risk factors. Patients older than the mean age of 53 years had a higher incidence of having multiple risk factors when compared with those younger than this age. Patients with kidney function impairment at baseline had a higher incidence of having multiple risk factors when compared with those with normal kidney function. Among the patients with no SCr investigation in the 3 months preceding a CECT, 64% had multiple risk factors. In the study population of 957 outpatients undergoing CECT, 52% had SCr measurements within 3 months before the study. An eGFR of less than 60 mL/min/1.73 m2 was found in 17% of the study population, and, in 0.6%, the eGFR was less than 30 mL/min/1.73 m2. Conclusion In an ambulatory outpatient population, many patients presenting for outpatient CECT studies will have risk factors for CIN or for kidney function impairment (low eGFR) at baseline. Kidney function assessment, therefore, is indicated in this patient population before CECT.

Publisher

SAGE Publications

Subject

Radiology Nuclear Medicine and imaging,General Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3