What is the Role of the Bacterium Propionibacterium acnes in Type 1 Modic Changes? A Review of the Literature-Reference-Cited by-同舟云学术

What is the Role of the Bacterium Propionibacterium acnes in Type 1 Modic Changes? A Review of the Literature

Published:2017-11 Issue:4 Volume:68 Page:419-424
ISSN:0846-5371
Container-title:Canadian Association of Radiologists Journal
language:en
Short-container-title:Can Assoc Radiol J

Author:

Georgy Mark¹²,Stern Mark²,Murphy Kieran³

Affiliation:

1. Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, California

2. Southern California Institute of Neurological Surgery, Escondido, California

3. Joint Department of Medical Imaging, University Health Network, Toronto, Ontario, Canada

Abstract

This review presents a summary of the pathology and epidemiology of Modic changes and the possible role of Propionibacterium acnes. This information is followed by a synthesis of the most recent clinical research involved in culturing the discs of patients with degenerative disc disease for the presence of bacteria. We also discuss a randomized controlled trial that investigates the effects of antibiotics on patients with chronic low back pain and type 1 Modic changes. We conclude with a brief discussion of the difficulties involved in this research and the significance of the findings.

Publisher

SAGE Publications

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1016/j.carj.2017.07.004

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