Comparative profile of cutaneous adverse events: BRAF/MEK inhibitor combination therapy versus BRAF monotherapy in melanoma

Author:

Sanlorenzo Martina,Choudhry Aditi,Vujic Igor,Posch Christian,Chong Kim,Johnston Katia,Meier Melissa,Osella-Abate Simona,Quaglino Pietro,Daud Adil,Algazi Alain,Rappersberger Klemens,Ortiz-Urda Susana

Publisher

Elsevier BV

Subject

Dermatology

Reference26 articles.

1. Improved survival with vemurafenib in melanoma with BRAF V600E mutation;Chapman;N Engl J Med,2011

2. Dabrafenib in BRAF-mutated metastatic melanoma: a multicenter, open-label, phase 3 randomized controlled trial;Hauschild;Lancet,2012

3. A first-in-human phase Ib study to evaluate the MEK inhibitor GDC-0973, combined with the pan-PI3K inhibitor GDC-0941, in patients with advanced solid tumors;LoRusso;J Clin Oncol,2012

4. Improved survival with MEK inhibition in BRAF-mutated melanoma;Flaherty;N Engl J Med,2012

5. MEK162 for patients with advanced melanoma harboring NRAS or Val600 BRAF mutations: a non-randomized, open-label phase 2 study;Ascierto;Lancet Oncol,2013

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