Pulmonary administration of phosphoinositide 3-kinase inhibitor is a curative treatment for chronic obstructive pulmonary disease by alveolar regeneration

Author:

Horiguchi Michiko,Oiso Yuki,Sakai Hitomi,Motomura Tomoki,Yamashita Chikamasa

Funder

Grant-in-Aid for Research Activity Start-up

Grant-in-Aid for Young Scientists

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference22 articles.

1. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary;Rabe;Am. J. Respir. Crit. Care Med.,2007

2. Stem cells are dispensable for lung homeostasis but restore airways after injury;Giangreco;Proc. Natl. Acad. Sci. U. S. A.,2009

3. Basal cells as stem cells of the mouse trachea and human airway epithelium;Rock;Proc. Natl. Acad. Sci. U. S. A.,2009

4. The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen;Adamson;Lab. Invest.,1974

5. Transformation of alveolar type 2 cells to type 1 cells following exposure to NO2;Evans;Exp. Mol. Pathol.,1975

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