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Drug-loaded sickle cells programmed ex vivo for delayed hemolysis target hypoxic tumor microvessels and augment tumor drug delivery

  • Published:2013-10 Issue:2 Volume:171 Page:184-192
  • ISSN:0168-3659
  • Container-title:Journal of Controlled Release
  • language:en
  • Short-container-title:Journal of Controlled Release

Author:

Choe Se-woon,Terman David S.,Rivers Angela E.,Rivera Jose,Lottenberg Richard,Sorg Brian S.

Funder

Bankhead–Coley Cancer Research Program

Florida Department of Health

National Institutes of Health

NHLBI

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference67 articles.

1. Delivery of molecular and cellular medicine to solid tumors;Jain;Adv. Drug Deliv. Rev.,2001

2. Sickle erythrocytes target cytotoxics to hypoxic tumor microvessels and potentiate a tumoricidal response;Terman;PLoS One,2013

3. D.S. Terman, Compositions and methods for treatment of neoplastic disease (2010), United States patent 7,803,637.

4. Vascular zip codes in angiogenesis and metastasis;Ruoslahti;Biochem. Soc. Trans.,2004

5. Sensitization of photohemolysis by hypericin and Photofrin;Al-Akhras;J. Photochem. Photobiol. B,1996
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