Engineering prolonged-acting prodrugs employing an albumin-binding probe that undergoes slow hydrolysis at physiological conditions

Author:

Sasson K.,Marcus Y.,Lev-Goldman V.,Rubinraut S.,Fridkin M.,Shechter Y.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference27 articles.

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3. Structure of serum albumin;Carter,1994

4. Albumin binding of insulins acylated with fatty acids: characterization of the ligand–protein interaction and correlation between binding affinity and timing of the insulin effect in vivo;Kurtzhals;Biochem. J.,1995

5. Albumin binding and time action of acylated insulins in various species;Kurtzhals;J. Pharm. Sci.,1996

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