A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog-Reference-Cited by-同舟云学术

A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog

Published:2012-06 Issue:3 Volume:160 Page:468-476
ISSN:0168-3659
Container-title:Journal of Controlled Release
language:en
Short-container-title:Journal of Controlled Release

Author:

Christensen Dennis,Henriksen-Lacey Malou,Kamath Arun T.,Lindenstrøm Thomas,Korsholm Karen S.,Christensen Jan P.,Rochat Anne-Francoise,Lambert Paul-Henri,Andersen Peter,Siegrist Claire-Anne,Perrie Yvonne,Agger Else Marie

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference70 articles.

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4. Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response;Henriksen-Lacey;J. Control. Release,2010

5. The vesicle size of DDA:TDB liposomal adjuvants plays a role in the cell-mediated immune response but has no significant effect on antibody production;Henriksen-Lacey;J. Control. Release,2011

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