FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designs

Author:

Larsen Maja Thim,Mandrup Ole A.,Schelde Karen Kræmmer,Luo Yonglun,Sørensen Karina Dalsgaard,Dagnæs-Hansen Frederik,Cameron Jason,Stougaard Magnus,Steiniche Torben,Howard Kenneth A.

Funder

Danish Innovation Fund

CEMBID

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference48 articles.

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2. Increased degradation of albumin in Cancer is not due to conformational or chemical modifications in the albumin molecule;Andersson;J. Surg. Res.,1990

3. Design of compounds having an enhanced tumor uptake, using serum-albumin as a carrier. 1;Sinn;Nucl. Med. Biol.,1990

4. Plasma protein (albumin) catabolism by the tumor itself - implications for tumor metabolism and the genesis of cachexia;Stehle;Crit. Rev. Oncol. Hematol.,1997

5. Design of compounds having enhanced Tumor uptake, using serum-albumin as a carrier. 2. Invivo studies;Schilling;Nucl. Med. Biol.,1992

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