Dose-response assessment of cerebral P-glycoprotein inhibition in vivo with [18F]MC225 and PET-Reference-Cited by-同舟云学术

Dose-response assessment of cerebral P-glycoprotein inhibition in vivo with [18F]MC225 and PET

Published:2022-07 Issue: Volume:347 Page:500-507
ISSN:0168-3659
Container-title:Journal of Controlled Release
language:en
Short-container-title:Journal of Controlled Release

Author:

Garcia-Varela Lara,Mossel Pascalle,Aguiar Pablo,Vazquez-Matias Daniel A.,van Waarde Aren,Willemsen Antoon T.M.,Bartels Anna L.,Colabufo Nicola A.,Dierckx Rudi A.J.O.,Elsinga Philip H.,Luurtsema Gert

Publisher

Elsevier BV

Subject

Pharmaceutical Science

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2. Novel intrinsic mechanisms of active drug extrusion at the blood-brain barrier: potential targets for enhancing drug delivery to the brain?;Löscher;Pharmaceutics.,2020

3. Functional expression and localization of P-glycoprotein at the blood brain barrier;Bendayan;Microsc. Res. Tech.,2002

4. Dysfunction of ABC transporters at the blood-brain barrier: role in neurological disorders;Gil-Martins;Pharmacol. Ther.,2020

5. Deposition of Alzheimer’s beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans;Vogelgesang;Pharmacogenetics.,2002

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1. Circadian Rhythms of the Blood-Brain Barrier and Drug Delivery;Circulation Research;2024-03-15

2. Cardiac PET Imaging of ATP Binding Cassette (ABC) Transporters: Opportunities and Challenges;Pharmaceuticals;2023-12-11

3. [¹¹C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier;Journal of Cerebral Blood Flow & Metabolism;2023-09-20

4. Quantification of P-glycoprotein function at the human blood-brain barrier using [18F]MC225 and PET;European Journal of Nuclear Medicine and Molecular Imaging;2023-08-08

5. Imaging blood–brain barrier disruption in neuroinflammation and Alzheimer’s disease;Frontiers in Aging Neuroscience;2023-03-17