Substitution of blood coagulation factor X-binding to Ad5 by position-specific PEGylation: Preventing vector clearance and preserving infectivity-Reference-Cited by-同舟云学术

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Substitution of blood coagulation factor X-binding to Ad5 by position-specific PEGylation: Preventing vector clearance and preserving infectivity

Published:2016-08 Issue: Volume:235 Page:379-392
ISSN:0168-3659
Container-title:Journal of Controlled Release
language:en
Short-container-title:Journal of Controlled Release

Author:

Krutzke L.,Prill J.M.,Engler T.,Schmidt C.Q.,Xu Z.,Byrnes A.P.,Simmet T.,Kreppel F.

Funder

International Graduate School Ulm

German Federal Ministry of Education and Research

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference53 articles.

1. Rapid and efficient clearance of blood-borne virus by liver sinusoidal endothelium;Ganesan;PLoS Pathog.,2011

2. Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity;Barouch;J. Immunol.,2004

3. International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: correlates of high Ad5 titers and implications for potential HIV vaccine trials;Mast;Vaccine,2010

4. Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma;Molnar-Kimber;Hum. Gene Ther.,1998

5. Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement;Xu;Nat. Med.,2013

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