The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder

Author:

Namkung HoORCID,Yukitake HiroshiORCID,Fukudome Daisuke,Lee Brian J.,Tian Mengnan,Ursini Gianluca,Saito AtsushiORCID,Lam Shravika,Kannan Suvarnambiga,Srivastava Rupali,Niwa Minae,Sharma Kamal,Zandi Peter,Jaaro-Peled Hanna,Ishizuka Koko,Chatterjee Nilanjan,Huganir Richard L.,Sawa AkiraORCID

Funder

National Institute of Mental Health

Brain and Behavior Research Foundation

National Alliance for Research on Schizophrenia and Depression

Publisher

Elsevier BV

Subject

General Neuroscience

Reference124 articles.

1. Genetics and genomics of psychiatric disease;Geschwind;Science,2015

2. The road to precision psychiatry: translating genetics into disease mechanisms;Gandal;Nat. Neurosci.,2016

3. The implications of the shared genetics of psychiatric disorders;O'Donovan;Nat. Med.,2016

4. Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia;medRxiv,2020

5. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology;Mullins;Nat. Genet.,2021

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