Poly(GR) in C9ORF72 -Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons
Author:
Publisher
Elsevier BV
Subject
General Neuroscience
Reference36 articles.
1. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons;Almeida;Acta Neuropathol.,2013
2. Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects;Almeida;Cell Rep.,2012
3. Accelerated high-yield generation of limb-innervating motor neurons from human stem cells;Amoroso;J. Neurosci.,2013
4. C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice;Atanasio;Sci. Rep.,2016
5. Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD;Boeynaems;Sci. Rep.,2016
Cited by 345 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Neurodegenerative disorders, metabolic icebergs, and mitohormesis;Translational Neurodegeneration;2024-09-06
2. NEK1 haploinsufficiency worsens DNA damage, but not defective ciliogenesis, in C9ORF72 patient-derived iPSC-motoneurons;Human Molecular Genetics;2024-09-02
3. Identification of selective and non-selective C9ORF72 targeting in vivo active siRNAs;Molecular Therapy - Nucleic Acids;2024-09
4. A robust evaluation of TDP-43, poly GP, cellular pathology and behavior in a AAV-C9ORF72 (G4C2)66mouse model;2024-08-27
5. Poly-GR Impairs PRMT1-Mediated Arginine Methylation of Disease-Linked RNA-Binding Proteins by Acting as a Substrate Sink;Biochemistry;2024-08-15
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3