Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
Author:
Funder
National Institutes of Health
National Institute on Aging
Stanford University
Publisher
Elsevier BV
Subject
General Neuroscience
Reference115 articles.
1. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60;Cao;Science,2001
2. Structural and Chemical Biology of Presenilin Complexes;Johnson;Cold Spring Harb. Perspect. Med.,2017
3. Intramembrane proteolysis by gamma-secretase;Steiner;J. Biol. Chem.,2008
4. A fast growing spectrum of biological functions of γ-secretase in development and disease;Jurisch-Yaksi;Biochim. Biophys. Acta,2013
5. Unraveling the complexity of γ-secretase;Wolfe;Semin. Cell Dev. Biol.,2020
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons;Neurobiology of Disease;2024-08
2. Exploring the multifaceted therapeutic mechanism of Schisanlactone E (XTS) in APP/PS1 mouse model of Alzheimer’s disease through multi-omics analysis;Frontiers in Microbiology;2024-07-09
3. Disruption of sphingomyelin synthase 2 gene alleviates cognitive impairment in a mouse model of Alzheimer’s disease;Brain Research;2024-07
4. PGC-1α in the hippocampus mediates depressive-like and stress-coping behaviours and regulates excitatory synapses in the dentate gyrus in mice;Neuropharmacology;2024-06
5. Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites;Developmental Cell;2024-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3